Month: July 2022

LiveMetric receives FDA 510 (k) for blood pressure monitors

LiveMetric has announced that it has received FDA 510 (k) clearance for its watch-like blood pressure monitor, LiveOne.

The cuffless device uses a sensor array placed above the radial artery to create a pressure wave. The waveform is analyzed by an algorithm to determine systolic and diastolic blood pressure and pulse rate. According to The FDA’s 510 (k) database, LiveOne, with a clear radial pulse intended for use in clinical settings for patients 27 years of age or older.

The Luxembourg-based company says LiveOne monitoring services will soon be available for people with high blood pressure or cardiovascular disease through healthcare, insurers and self-insured employers.

Kelly Benning, vice president of Livemetric, said in a statement, “The LiveOne device is designed to address the global epidemic of high blood pressure by providing meaningful, deeply personalized health information to patients and providers so that action can be taken in real time.”

“As easy as wearing a watch, the LiveOne device will change how high blood pressure and cardiovascular disease are managed and treated by offering people a thorough understanding of how their lifestyle, behavior and medications affect their blood pressure. We are focused on bringing this. করছি Millions of users across our customer-based channels. “

Greater trend

Another company behind the watch-like blood pressure device is Actia, which has announced that it was Received a European CE mark in early 2021. The Swiss startup raised এ 17.5 million in series A funding in November. Although it is not yet commercially available in the United States, Actia announced in January that it would conduct a study with Brigham and Women’s Hospital in Boston.

Omron Health Care In 2018 it first received FDA clearance for its HeartGuide wearable blood pressure monitor.

Meanwhile, Samsung has included Blood pressure monitoring on its Galaxy smartwatches in countries where it has regulatory approval. Although ECG tracking has been cleared by the FDA, blood pressure monitoring is not available in the United States.

Apple is interested in monitoring blood pressure for its watches. However, as The technology is not expected to be ready by 2024, Bloomberg reported in April.

The monkeypox vaccine rollout has been plagued by problems in New York

Paul Chaplin, chief executive of Bavarian Nordic, which makes the vaccine, said Thursday that research shows that a single dose provides “strong protection”. Dr Bassett, however, said complete protection from the vaccine would be available two weeks after the second dose.

Health officials in New York say people who fall into one of the different categories are eligible for the vaccine:

  • People who have been in contact with monkeypox for the past 14 days.

  • Those who are gay, bisexual, transgender, and members of other communities of men who have had sex with men, and who have been in close or skin contact with others in the last 14 days, have recently been at higher risk of coming into contact with monkeypox. Areas where monkeypox is spreading.

  • People who have had skin-to-skin contact with someone who has experienced monkeypox activity on a social network, including those who have sex with men, and who meet partners through an online website, digital app or social event such as a bar or party.

Partly because the categories are wide, the demand for vaccines is extremely high. All 2,500 or more appointments on Wednesday were gone within minutes, health officials said.

There was a lot of frustration with access to the vaccine on Wednesday, as people spent hours without knowing if they had missed the rollout or if more doses were coming.

Eugene Resnick, who works as a spokesman for the Metropolitan Transportation Authority, said he spent nine hours refreshing the city’s webpage and was finally able to make an appointment when a second set was released just before 7 p.m.

“I’m frustrated, angry, frustrated with the health department,” he said. “I am an insider working in the government. I can’t imagine it being accessible to a regular person who isn’t on Twitter. “

Joseph Osmundsson, a microbiologist and queer activist who helps increase access to vaccines, says the city has done the right thing by opening a clinic in Harlem, in addition to Chelsea, to give the vaccine, but it has to be done there. Make more urgent efforts to get more vaccine supplies in the city soon.

“At every level, there is such frustration within the community,” Mr. Osmundson said. He said his acquaintances were trying to be cautious but were growing increasingly angry at the lack of urgency to protect the gay community in particular, which he felt was: “We feel we are being left behind and then blamed for the spread.”

No. 2 Theranos executive has been convicted of 12 counts of fraud.

SAN JOSE, California – Ramesh Balwani, the former chief executive of Theranos, was convicted Thursday of 12 counts of fraud, a verdict that was more serious than his co-conspirator, Elizabeth Holmes, and consolidated failed blood. – Start-up testing as the ultimate Silicon Valley warning story.

Mr. Balwani and Mrs. Holmes, who together pushed Theranos to new heights with a promise to revolutionize healthcare, are the most prominent technology executives in a generation accused of fraud and convicted. A jury of five men and seven women took 32 hours to give a verdict, convicting Mr. Balwani, also known as Sunny, of 10 counts of wire fraud and two counts of conspiracy to commit wire fraud.

Mrs Holmes was convicted of four counts of fraud in January and four were acquitted; The other three charges were dismissed after the jury failed to reach a consensus. He has appealed against the verdict and Mr Balwani is expected to do the same.

In both cases there is a complete digestive tract to see if they have exaggerated the power of the Theranos blood-testing machine to appeal to investors and consumers, when the products did not actually work.

Each count carries a maximum sentence of 20 years in prison. Mr Balwani and Miss Holmes are expected to be sentenced together in September.

This is a developing story. Check back for updates.

Callie Huang Contributing Reporting.

7 mindfulness-based strategies to stop leaning towards depression

In an era of gun violence, war and political divisions, following endless news can become irresistible. And in the midst of our many ongoing challenges – epidemics, climate change, economic uncertainty – it is understandable to feel sad, angry and worried.

As a clinical psychologist who specializes in giving people the tools to deal with intense emotions, I know how positive it can be to take a deeper care of our world – or just how difficult it can be to maintain balance. Some of my clients say they can’t stop doomscrolling, others engage in unhealthy behaviors to secure it, and many bounce between the two extremes.

But it is possible to anchor yourself if you feel like you are falling into despair about the state of the world. I rely on these seven mindfulness-based strategies to keep me and my clients grounded.

If you can properly label the emotion you are feeling at the moment, you can reduce its energy in your body and brain. Name the emotion you are feeling, be it sadness, fear, anger, hatred or guilt – and how intensely you are feeling it. Say it out loud, use a mood tracking app like Daily, Reflectively or Moodnotes or write down your feelings in a journal.

Try not to wait until your feelings come to the top though. Practice naming as soon as your emotions come. Tracking their intensity allows you to slow down before reaching a boiling point and can lose yourself in anxiety or rumors, hitting someone or reaching for a substance unscathed.

Melanie Hernandez, a psychologist at VA Puget Sound Health Care System and author of “Treating Trauma in Dialectical Behavior Therapy”, says that if you try to avoid your feelings, they will intensify. When you are emotionally affected by a news story, take a moment to notice what you are thinking, doing, and feeling in your body. Choose what works best for you right now – whether it’s creating a window to feel your emotions for a few minutes, without trying to change them, or, if you’re in the middle of an important task, plan to revisit the painful news. Time you can mourn.

One way to improve your ability to sit with emotions is to remember that they can fluctuate quickly. One exercise that helps my clients stop worrying about their feelings is watching a series of short, emotional scenes – a death scene from “The Champ” and then a snippet from Farrell Williams’ “Happy” music video. “If you try it, you can tear yourself apart in a moment, then dance or laugh in your chair. The goal is to see how that same transient feeling can be applied to different types of emotions when you are present throughout the day.

Understandably, after a tragedy, it can also feel tempting to shrink the chances of your life to avoid painful emotions. For example, after learning of the widespread violence in a supermarket, as we have seen in the case of the horrific Boulder and Buffalo shots, it is normal to feel uncomfortable going to the grocery store. Remember that allowing yourself to feel your emotions with fear will eventually improve your anxiety when you get back to routine, says Dr. Hernandez.

You can feel driven to make a difference and help without over-identifying the other person’s pain. “We are taught that the way to help others is through empathy, but it can be a trap,” said George Everly Jr., a professor at the Johns Hopkins School of Public Health who specializes in crisis intervention and resilience.

In order to reduce the burning sensation among humanitarian aid workers, Dr. Everly encourages them to take perspectives or try to understand the world from the perspective of others instead of absorbing themselves in their emotions, rather than blurring the line between what they are feeling. Your experience.

“There is a difference between being aware and being immersed and overwhelmed,” says Sharon Salzburg, a leading mindfulness teacher and author of “Real Change: Mindfulness to Hill Oursells and the World”.

A study of more than 7,500 physicians found that understanding and acknowledging patients ’emotions reduced burnout, while excessive exposure to their patients’ experiences predicted mental fatigue among physicians. It requires practice, but if you find yourself feeling overwhelmed, try to take a few breaths and then try to change to a more cognitive form of anxiety as opposed to fully participating in grief.

By considering ways to help others, you will regain some control in a world that may feel overwhelming when it comes to improving your own well-being. Doing things intentionally and repeatedly, such as donations, volunteering, or being politically involved, reduces a person’s risk of falling into depression and increases happiness.

“When we get together and wake up with a positive, real action, it’s almost impossible to fall into despair,” said Shelley Tigielski, an activist and author of “Sit Down to Rise Up.”

Spend some time thinking about the factors that make sense to you the way you want to contribute. As we work to improve injustice in the world, “our empathy and our efforts must be balanced with the wisdom that things can take time. They may take a long time, but sometimes our efforts are planted with a seed, ”said Mrs. Salzburg.

It may feel normal to use dramatic statements like “I’m broken” when something terrible happens in the world. This is especially true on social media, where extreme language can be legitimized by other people “liking” or commenting. But our words and interpretations have a powerful effect on our feelings and behavior.

While it’s helpful to allow ourselves to respect our feelings, our emotions intensify when we over-describe situations that are already painful. Catastrophic thinking can trigger or exacerbate negative emotions in many people. So consider replacing thoughts or phrases such as, “The world is falling apart”, “I need to do something to improve X.”

Resilience, the ability to work after a stressful event, often depends on adding positive emotions and actions to your day to improve your ability to cope with challenges. Connect with people who inspire you and schedule hobbies that can get you excited. Protecting your mental health is not selfish; This enables you to be your best version, not the burn-out version, said Dr. Everly, who takes the time to exercise even while on a disaster relief mission.

Aside from adding activities that encourage happiness, practice engaging in moments when positive emotions naturally arise in your day, be it your morning coffee or spending time with someone you love.

“When the news cycle is affected by horrible things, we can lose good eyesight in the world and in our own lives,” Dr. Hernandez said.

But if you are struggling to find moments of peace and find yourself experiencing grief or anxiety that is affecting your ability to work, contact a therapist who can provide you with evidence-based tools to improve your well-being.

Think about the specific time of day, say morning and mid-afternoon, when you want to keep it up instead of constantly scrolling through the news or keeping it running in the background. Taking a break doesn’t mean you’re not taking care; It’s about hitting the break so you can go back to tackling the world’s challenges and trying to make a real difference.

It is also important to stay connected to the factors that are important to us in a relatively quiet time. “We feel intense pain, then forget,” Mrs. Salzburg said. He suggests we find ways to appear for important reasons, even if they are not at the top of our news feed.

Allow yourself to feel pain and joy without getting stuck. In this way let your emotions contribute to the real healing. Dr. Harnond reminded me of an analogy that Marsha Linehan, a psychologist and pioneer of mindfulness-based behavioral therapy, taught: You can go to the cemetery without building a house there.


Jenny Titz is an assistant clinical professor of psychiatry at the University of California, Los Angeles, and author of several books, including one on upcoming stress.

The emergence of remote patient observation reveals the true value of telehealth

Beyond enabling physician-patient relationships to continue, telehealth benefits are now leading to the adoption of many aspects of care that have been critically hampered by epidemics – particularly preventive health care, remote patient monitoring, and chronic disease management.

While physicians derive great value from the flexibility and efficiency enabled by these digital health tools, patients can also take a more active role in their adoption. As they invest more in their own care and wellness management, the use of telehealth technology, such as wearable devices, will enable them to share their health data with healthcare professionals in a more innovative way.

Chronic disease management

Due to chronic conditions such as diabetes and heart disease, especially in the aging population, digital collection and data monitoring is a major way where physicians can create a more complete picture of their patients ’health. Real, continuous, long-term readings can help diagnose difficult and potentially serious conditions such as atrial fibrillation (AF).

Many digital health experts see the use of preventive components in telehealth solutions as a key trend for 2022. The range of health data that can be captured at home enables doctors to change therapy in advance, take preventative measures, and treat tailors. Admit the patient to the hospital, and monitor the patients and check for post-discharge changes in their health. In some cases, this data may be managed by an extensive care team, which may go to the doctor if the patient’s condition changes.

Remote patient observation

Remote patient monitoring can bring an equilibrium to communities that have traditionally had difficulty accessing healthcare, ensuring that all patients receive the high-quality, uninterrupted care they need for their condition.

From a patient’s perspective, telehealth tools that can help improve compliance by triggering medication alertness. These can also be used to communicate changes in care and physician advice in response to lessons. Some digital health leaders have even identified an emerging role of telehealth in recruiting a wide range of patients in clinical trials that they do not normally participate in.

Discreet device

The use of remote monitoring devices in this rapidly evolving landscape can help increase the rate of diagnosis and streamline treatment and care for a range of chronic conditions. CART-I (Cardio-Tracker) from Sky Labs, for example, has already received CE-MDD approval in Europe. Wearing as a ring and connected to the cloud, it generates analysis reports, acquires data to plan therapy, and sends an alert if the patient’s condition changes

Jack Lee, CEO of Sky Labs, said: “This will help patients with chronic disease manage a variety of conditions, including heart failure, manage the entire chronic disease cycle from screening to diagnosis and follow-up, and allow us to accurately collect data on an increasingly large scale. .-Scale decentralized trial. “

Practice management software secures Tebra $ 72M

Practice management software company has secured more than $ 72 million in equity and debt financing from Tebra Golub Capital, valued at more than $ 1 billion.

What does this mean?

Tebra is a fruit Kareo, which offers clinical and financial software, and the recent integration between PatientPop, which provides tools to increase patient engagement and practice. The deal closed in November.

The joint venture includes the creation of a medical practice website and advertising of its services, online schedules and patient reminders, telehealth, an EHR, billing and payment, as well as data analysis products.

Tebra Capital will use its post-consolidation plans to accelerate, such as growing market share, developing and launching products as a joint venture, and branding new entities.

“With this new investment from Golub Capital, we will be able to accelerate Tebra’s mission to unlock improved healthcare by helping independent practices bring modernized care to patients everywhere,” CEO and co-founder Dan Rodriguez said in a statement.

“Together, we will expand our market reach and launch new solutions, attract more patients, help more physicians with digital tools and support to get paid faster and manage their practice more efficiently.”

Snapshots of the market

Patientpop It raised $ 50 million from the Series C fund in 2020 and $ 25 million in 2018. According to Crunchbase, Kareo last collected around $ 10 million in 2018. It also acquired billing-automation company PatientlySpeaking last year and patient-communication equipment DoctorBase in 2015.

Another company in the practice management space, NexHealth, has announced that it has closed a The $ 125 million Series C funding round in April brought the company to a 1 billion valuation. It provides tools for online scheduling, marketing and patient engagement.

Patient communication platform Luma Health Scored $ 130 million late last year. Change Healthcare recently unveiled a new suite of engagement tools designed in collaboration with Lumar.

Meanwhile, SocialClimb, which focuses on marketing medical practice, Announced an increase of $ 12 million early last year.

Montana Clinics Restrict Access to Abortion Pills for Out-of-State Patients: Shot

A planned parenthood at the Helena Montana Clinic is among those who have recently changed its policies to limit the distribution of abortion pills to effectively treat patients in the state without abortion bans.

Matt Volz / Kaiser Health News


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Matt Volz / Kaiser Health News


A planned parenthood at the Helena Montana Clinic is among those who have recently changed its policies to limit the distribution of abortion pills to effectively treat patients in the state without abortion bans.

Matt Volz / Kaiser Health News

The four states bordering Montana have “trigger laws” in place or pending that the U.S. Supreme Court has ended federal protection for abortion, making the conservative Big Sky Country an unlikely haven for women seeking to terminate their pregnancies.

But Montana’s chances of becoming an abortion shelter have dwindled – not by lawmakers and governors whose efforts to restrict abortions have been hampered by the state’s constitutional right to privacy, but by operators of at least four of the state’s five clinics who can already take abortion pills. To do.

Officials at the Planned Parenthood of Montana, which operates three of the four clinics, say the goal is to ensure that they and their patients from the state, including trigger bans – are prohibited or restricted by abortion laws that were designed to take effect. Rowe vs. Wade Has been injured – protected from criminal charges and lawsuits. But the change in policy is another complication for women in neighboring states, such as South Dakota, who want to end the pregnancy and face the rapidly narrowing field of alternatives.

“It was a state we hoped it would be found,” said Kim Floren, director of the Justice Through Empowerment Network, a South Dakota abortion fund that provides financial assistance to people who need the procedure. “Right now, it’s worse news on top of worse news.”

Patients often prefer drug abortions over surgical abortions because they are cheaper, take less time to the clinic and offer them more privacy and more control. The most common type of drug abortion is a two-part pill procedure: the first is taken at the clinic if a personal visit is required; The second is usually taken at home. In many states, medications may be sent to the patient after a telemedicine appointment.

In 2020, drug abortions accounted for more than half of all abortions in the United States for the first time, according to the Gutmachar Institute, a research organization that supports the right to abortion. Advocates hope that drug abortion will become the goal of the new state law. In South Dakota, a law banning abortion through telemedicine went into effect July 1.

A transferred legal landscape

The change in Planned Parenthood policy in Montana is a response to changes in the legal landscape, said Jennifer Sandman, public policy lawsuit for the National Agency for Planned Parenthood and senior director of law. “People are working in a state of extraordinary chaos and fear that the Supreme Court has abandoned us and in some states has been aroused by threats from anti-abortion politicians,” Sandman said.

Montana’s Planned Parenthood decided June 30 that it would not provide abortion pills to patients in their clinics in Billings, Great Falls and Helena in states where the Trigger Act has been enacted. At the time, bans were in place in South Dakota, Arkansas, Missouri and Oklahoma, but Planned Parenthood officials said they saw a significant number of patients from South Dakota. Officials did not respond when asked how many South Dakota patients would be infected.

Montana’s other neighbors – Idaho, Wyoming and North Dakota – also have trigger laws, but they have not yet been enacted.

Martha Fuller, president of Montana Planned Parenthood, wrote in an internal memo that the risks of cross-state provision of services were unclear, citing concerns about the potential for civil and criminal action against drug suppliers that terminate human pregnancies. From states with effective sanctions. The memo was posted on Twitter by a freelance journalist and was later deleted. Planned Parenthood officials have confirmed the policy change.

Montana’s three planned parenthood clinics will continue to provide abortion procedures to residents outside the state. “At this point, we believe this is the best way to ensure that out-of-state patients are not afraid to access their necessary follow-up care because of intimidation and intimidation by extreme anti-abortion politicians,” said Laura Terrell, a spokeswoman for Montana Planned Parenthood.

The planned parenthood decision came just days after Missoulian reported that Missoula’s Blue Mountain Clinic would only offer drug abortions to people with Montana addresses. Clinic officials did not answer questions by phone or email.

The fifth clinic to provide abortions in Montana, Whitefish’s All Family Healthcare, declined to answer questions about its policy for out-of-state patients.

Fuller said in his memo that the planned parental policy may change as the legal risks have become clear. The memo did not mention that Montana’s status as a state with legal access to abortion could change soon.

Montana’s Republican-majority legislature and Republican governor passed four state laws in 2021 to limit abortion, but three were blocked by a judge who quoted a 1999 state Supreme Court ruling as saying abortion was a right under the Montana constitution. State Attorney General Montana is urging the Supreme Court to reverse that precedent and enforce the laws. There is a pending decision.

The Montana Chapter is not the only planned parent network that is temporarily changing its policy on abortion pills due to the chaotic consequences of the US Supreme Court’s action. Planned Parenthood North Central States, which arranges drug abortions in Minnesota, Iowa and Nebraska, says patients must take the pill in states where abortion is legal.

The South Dakota Trigger Act makes it a crime to prescribe or administer a substance that causes abortion, but it does not target aborted people. Floren, of the Justice Through Empowerment Network, said there were still fears that South Dakotans could be investigated or charged if they were caught with pills in the state or had to go to their medical provider because of a complication. “A lot of people really like that method and now it’s taking people’s choices again,” he said.

“Heartbreaking decision”

Providers in other states that have become islands for legal abortion do not agree with policies restricting access to out-of-state patients. In Colorado, Dr. Nancy Fang, an OB-GYN at Denver’s Comprehensive Women’s Health Center, said she understands caution in the face of the uncertainty surrounding the state’s abortion ban. But, he said, restricting access would hurt patients and increase pressure on other clinics that continue to provide drug abortions.

“I think it’s really influential on the patient because it further limits their autonomy for access to healthcare, not being able to access a safe alternative based on where they are coming from,” Fang says.

Parenthood of the Rocky Mountain, planned in parts of Colorado, New Mexico, Wyoming and Nevada, does not plan to change its policies, although spokesman leader Meltzer said his organization supports other partners such as Montana to make “heartbreaking decisions.”

“We serve all patients equally, those who live in our own community and those who escape from the abominable restrictions in their own state,” Meltzer said.

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Abortion methods are considered to be more effective than abortion pills, although they are more aggressive by their nature. The procedure requires the patient’s cervix to be dilated using surgical equipment, and patients often take anti-anxiety medications or intravenous sedatives. With pills, those who have been abused by their partners can say that they have had an abortion, since the amount of bleeding and other symptoms are similar.

Planned Parenthood plans to expand an organization called Just the Pill, limiting the distribution of abortion pills in Montana. Patients can make telehealth appointments with medical providers from Just the Peel and then take the pills in Montana, Minnesota, Wyoming or Colorado.

Following the Supreme Court decision, the agency said it would send a fleet of mobile clinics to state lines to provide services to women in the states, including abortion restrictions. “By working at state borders, we will reduce the travel burden for patients in states with restrictions or severe limits,” the company said in a statement.

Floren said he hopes Just the Peel will continue to provide services for South Dakotans. The Justice Through Empowerment Network has seen an influx of grants and volunteers, and Floren says the abortion fund is preparing to organize people to attend the upcoming special legislature session where she hopes lawmakers will target abortion aid donors or distributors.

KHN correspondents Rai Ellen Beechel and Erica Zurek contributed to this report.

Lunit Cathy Integrates AI Book X-Ray Solution with Life Insurance

South Korean AI company Lunit has signed a licensing agreement with Taiwan-based insurance company Cathay Life Insurance to integrate the X-ray software in its AI book into the next underwriting workflow.

Why it matters

Taiwanese insurers review about 30,000 chest X-ray images each year, and this requires a solution that reduces reading time.

Two years ago, it tapped Lunit for a proof-of-concept study to show the value of his chest X-ray analysis software Insight CXR. The software was evaluated for its impact on the Cathay Life review process in terms of profitability, efficiency and accuracy.

In the study, X-ray images of about 200 books were used as samples in a previous analysis using Lunit’s software. After an internal review by Cathay Life’s resident radiologists, it was found that the AI ​​tool showed an overall accuracy rate of 90%, with a detection rate of 83% in the positive case and 92% in the negative case.

In addition, hiring Lunit AI increases the insurance provider’s reading accuracy by up to 20% and reduces its overall reading time by up to 90%.

“Lunit’s AI algorithm accurately detects small nodules and pulmonary fibrosis, which is not easy to distinguish on chest radiographs,” added Cathy Life’s underwriting department.

“This is the first time Lunit’s AI has officially merged with the insurance underwriting process and this proves that our solutions can bring value to the workflow beyond hospital settings,” said Brandon Suh, CEO of Lunit.

Greater trend

The announcement follows Lunit’s latest partnership in Thailand, setting up both its Insight CXR and mammography tool Insight MMG. Bamrungrad International Hospital. Together with Fujifilm Thailand, it will provide AI solutions to hospitals using Microsoft Azure.

Lunit is set to make its debut on the Korean Exchange this month after submitting a registration statement for an initial public offering in June.

In other news, ICT provider Dr. Fujitsu and Salesforce Japan, a customer relationship management services company, have partnered to develop new digital solutions for the insurance sector. Specifically, Fujitsu will develop a personalized healthcare service to detect symptoms of specific diseases using Fujitsu computing as a service while Salesforce will use its healthcare offers such as its CRM system Health Cloud.

Researchers at the Indian Institute of Technology have developed an AI tool for detection

Researchers at the Indian Institute of Technology in Madras have come up with a new AI prediction tool that can detect cancer-causing genes in individuals.

What does this mean?

Pivot dubbed, the AI ​​tool is based on a prediction model that uses information on mutations due to mutated gene expression, gene expression and variation in gene numbers, and confusion in biological networks.

The machine learning model is able to classify these genes as tumor suppressor genes, oncogenes or neutral genes.

A. The study, the results of which were published in the peer-reviewed journal Frontier in Genetics, found that PIVOT successfully predicted both oncogenes and tumor-suppressing genes such as TP53, and PIK3CA, and new cancer-related genes, such as PRKCA, SOX9, and PSMD4. .

Researchers have so far developed AI prognosis models for three cancers: breast invasive carcinoma, colon adenocarcinoma, and lung adenocarcinoma. According to a press release, they plan to create more models for other types of cancer.

In addition, the research team is compiling a list of cancer-causing genes to help identify appropriate drugs for patients based on their cancer profile.

Why it matters

Uncontrolled cell growth that leads to cancer is caused by oncogenes or mutations in tumor suppressor genes or both. However, according to IIT-Madras researchers, not all mutations result in cancer.

They said that identifying the genes responsible for the onset and progression of cancer in patients helps determine the appropriate combination of drugs and therapies for their recovery.

“As cancer treatment is increasingly moving towards personalized drugs, such models that make a difference in patients can be very effective,” commented Dr. Kartik Raman, research team member and associate of IIT-Madras Bhupath and Jyoti Mehta School of Biosciences. Professor 7

Although there are existing tools that can also identify cancer genes, they use unsupervised learning and predict them based on the presence and absence of mutations in that gene.

The IIT-Madras study on PIVOT, according to the research team, was the first to use supervised learning and consider the effective effects of mutations in making predictions.

Snapshots of the market

There have been recent efforts across Asia-Pacific to detect and predict cancer using AI technology. Last month, the cancer care platform Karkinos Healthcare has partnered with American oncology diagnostic firm C2i Genomics to promote AI-enabled cancer screening in India. The latter offers a diagnostic test that uses AI to identify the amount of recurrent cancer.

ICT provider Fujitsu is working on a research project with Southern Tohoku General Hospital in Japan to create an AI solution that detects pancreatic cancer from CT scans at an early stage.

A research team two years ago The National University of Singapore has come up with a cancer scorecard, a panel of 29 selected genes that help identify cancer. It was created using big data and predictive analysis of biopsies obtained from more than 30,000 patients.

On record

“The field of precision drug research is still at an early stage. PIVOT helps push these boundaries and presents the possibility of experimental research based on identified genes,” said Malvika Sudhakar, a research team member and IIT-Madras research scholar.

ResApp gets 510 (k) clearance for mobile sleep apnea test slipcheck

ASX-listed ResApp Health SleepCheckRx has received 510 (k) clearance from the US Food and Drug Administration for its mobile sleep apnea screening app.

Introduced Two years ago, SleepCheck was a home test for adults who are at risk of moderate to severe obstructive sleep apnea. It screens for conditions by analyzing the breath and snoring sounds recorded over the phone.

It has been approved in the United States as a prescription-only software-a-medical device on Apple smartphones. To download the app from the Apple App Store, patients need to secure a specific code from their care providers.

Raceup plans to ask for a further 510 (k) clearance for slipcheck on Android phones “in the future”, according to a media release.

Why it matters

According to a study published in the American Journal of Epidemiology, in the United States, sleep apnea is the most common sleep disorder affecting more than three out of 10 people and about two out of every 10 women. Aging population and increasing rates of obesity are increasing the cases. Among people with this condition, up to 80% are unaware of having sleep apnea, a Frost & Sullivan report found.

“More than 20 million American adults suffer from sleep apnea and most don’t know they have it. This release opens up a significant market opportunity for ResApp. Using SleepCheckRx, physicians will be able to conveniently test their patients and quickly Helps patients take the first step in their treatment, ”said Tony Keating, CEO and managing director of Raceup.

Greater trend

ResApp applied for a 510 (k) clearance for slipcheck in October last year. In a home clinical trial involving 220 patients, Slipcheck was found to correctly identify 89% of patients with moderate to severe obstructive sleep apnea with 77.6% specificity. In addition to the United States, the app is also commercially available in Europe and Australia.

In other news, ResApp announced Tuesday that patents for cough detection technology have been approved in Australia and Japan. The mentioned technology enables its respiratory diagnostic test ResAppDx and its cough counting software ResAppCC.

Last month, ResApp revealed that Pfizer had revised its offer to buy the company in its entirety. From A $ 0.207 per share to a company valued at around A $ 180 million ($ 122 million), the pharma giant is now offering A $ 0.146 per share, which represents an equity value of A $ 127 million ($ 86 million) – still a higher takeover valuation than the initial one. A $ 100 million ($ 68 million).